Introduction to Parenteral Dosage Form

Topic #1 

Injection:- 

➡️ Injection are sterile , pyrogen free Preparation intended to be Administered parenterally.

➡️ The term Parenteral refers to the injectable route of administration.

        Greek words: 

Para ➡️ outside 

Enteron ➡️ intestine 

Denotes route of administration other than oral route. 

➡️ Pyrogen fever producing organic substance arising from microbial contamination are responsible for many other febirle reactions in patient following intravenous injections.

➡️ In general Parenteral routes are used when rapid drug action is desired as in emergencies when the patient is unco-operative , unconscious or un able to accept or tolerate oral medication or when drug the drug is itself infective by others route.

➡️ With the exception of insulin injection which are commonly self administrated by diabetics patients , most injection are Administered , by the physician , physician assistant or nurse. In the course of medical treatment. 

➡️ This injection are employed mostly in the hospital extended care facility and clinic and less frequently in the home.

➡️ An exception is home health care program in which the health professional pay schedule visits to patients at home providing needed treatment including intravenous medications.

➡️ These program enable patient who do not require bor un able to pay for more expensive hospitalizations to remain at home while receiving appropriate medical care.

➡️ The Pharmacist supplies injectable Preparation to the physician and nurses as required for the use in the institutional setting , clinic , offices , or home health care program.

➡️ Perhaps the earliest injectable drug to receive official recognition was HYPODURMIC MORPHINE solution which appeared first in the 1824 added to the 1867 in British Pharmacopeia and in 1888 in 1st edition of American National Formulary .

➡️ Today 100s of drugs and drugs products are available for parenteral administration.

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