ATORVASTATIN

 Trade Names: atrolip , Atorva, Atorex Lipitor, Torvast, Totalip, Ator, Tahor, Statinor, Torva, Atoris, Sortis, Torvacard, Tulip. 


Classification: Atorvastatin is a pyrrole and heptanoic corrosive derivative,hydroxymethylglutaryl-coa reductase inhibitor (statin), and anticholesteremic specialist 


Indications: Hyperlipidemia like essential hypercholesterolemia and blended dyslipidemia (raised LDL-cholesterol and fatty oil), hypertriglyceridemia, Familial Hypercholesterolemia. 


Counteraction of Cardiovascular Disease. 


Mechanism of Action: Atorvastatin seriously represses hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the chemical which catalyzes the change of HMG-CoA to mevalonate, a critical advance in cholesterol union. This specialist expands the quantity of LDL receptors on hepatic cell surfaces, improving the take-up and catabolism of LDL and decreasing LDL creation and the quantity of LDL particles, and brings down plasma cholesterol and lipoprotein levels 


Side Effects: The most generally revealed unfriendly responses include: nasopharyngitis (irritation of the nasal entries, torment in the throat), nose drain, joint agony, muscle torment, back torment, loose bowels, and urinary parcel contamination and consumption of CoQ10.

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